31 تير 1387
کتاب ویروس شناسی(اصول ها و کاربردها) Virology: Principles and Applications
Virology: Principles and Applications
Edition: 1st
Author(s): John Carter (Liverpool John Moores University, UK); Venetia Saunders (Liverpool John Moores University, UK)
ISBN10: 0470023864
ISBN13: 9780470023860
Format: Hardcover
Pub. Date: 8/1/2007
Publisher(s): WILEY
Page: 383
New Price $165.75 (See )
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Preface.
Abbreviations used in this book.
Greek letters used in this book.
Colour coding for molecules.
1 Viruses and their importance.
1.1 Viruses are ubiquitous on Earth.
1.2 Reasons for studying viruses.
1.3 The nature of viruses.
1.4 The remainder of the book.
2 Methods used in virology.
2.1 Introduction to methods used in virology.
2.2 Cultivation of viruses.
2.3 Isolation of viruses.
2.4 Centrifugation.
2.5 Structural investigations of cells and virions.
2.6 Electrophoretic techniques.
2.7 Detection of viruses and virus components.
2.8 Infectivity assays.
2.9 Virus genetics.
3 Virus structure.
3.1 Introduction to virus structure.
3.2 Virus genomes.
3.3 Virus proteins.
3.4 Capsids.
3.5 Virion membranes.
3.6 Occlusion bodies.
3.7 Other virion components.
4 Virus transmission.
4.1 Introduction to virus transmission.
4.2 Transmission of plant viruses.
4.3 Transmission of vertebrate viruses.
4.4 Transmission of invertebrate viruses.
4.5 Permissive cells.
5 Attachment and entry of viruses into cells.
5.1 Overview of virus replication.
5.2 Animal viruses.
5.3 Bacteriophages.
6 Transcription, translation and transport.
6.1 Introduction to transcription, translation and transport.
6.2 Transcription of virus genomes.
6.3 Transcription in eukaryotes.
6.4 Translation in eukaryotes.
6.5 Transport in eukaryotic cells.
6.6 Transcription and translation in bacteria.
7 Virus genome replication.
7.1 Overview of virus genome replication.
7.2 Locations of virus genome replication in eukaryotic cells.
7.3 Initiation of genome replication.
7.4 Polymerases.
7.5 DNA replication.
7.6 Double-stranded RNA replication.
7.7 Single-stranded RNA replication.
7.8 Reverse transcription.
8 Assembly and exit of virions from cells.
8.1 Introduction to assembly and exit of virions from cells.
8.2 Nucleocapsid assembly.
8.3 Formation of virion membranes.
8.4 Virion exit from the infected cell.
9 Outcomes of infection for the host.
9.1 Introduction to outcomes of infection for the host.
9.2 Factors affecting outcomes of infection.
9.3 Non-productive infections.
9.4 Productive infections.
10 Classification and nomenclature of viruses.
10.1 History of virus classification and nomenclature.
10.2 Modern virus classification and nomenclature.
10.3 Baltimore classification of viruses.
11 Herpesviruses (and other dsDNA viruses).
11.1 Introduction to herpesviruses.
11.2 The human herpesviruses.
11.3 The herpesvirus virion.
11.4 HSV-1 genome organization.
11.5 HSV-1 replication.
11.6 Latent herpesvirus infection.
11.7 Other dsDNA viruses.
12 Parvoviruses (and other ssDNA viruses).
12.1 Introduction to parvoviruses.
12.2 Examples of parvoviruses.
12.3 Parvovirus virion.
12.4 Parvovirus replication.
12.5 Other ssDNA viruses.
13 Reoviruses (and other dsRNA viruses).
13.1 Introduction to reoviruses.
13.2 Rotavirus virion.
13.3 Rotavirus replication.
13.4 Other dsRNA viruses.
14 Picornaviruses (and other plus-strand RNA viruses).
14.1 Introduction to picornaviruses.
14.2 Some important picornaviruses.
14.3 The picornavirus virion.
14.4 Picornavirus replication.
14.5 Picornavirus recombination.
14.6 Picornavirus experimental systems
14.7 Other plus-strand RNA viruses.
15 Rhabdoviruses (and other minus-strand RNA viruses).
15.1 Introduction to rhabdoviruses.
15.2 Some important rhabdoviruses.
15.3 The rhabdovirus virion and genome organization.
15.4 Rhabdovirus replication.
15.5 Other minus-strand RNA viruses.
15.6 Viruses with ambisense genomes.
15.7 Reverse genetics.
16 Retroviruses.
16.1 Introduction to retroviruses.
16.2 Retrovirus virion.
16.3 Retrovirus replication.
16.4 Examples of retroviruses.
16.5 Retroviruses as gene vectors.
16.6 Endogenous retroviruses.
17 Human immunodeficiency viruses.
17.1 Introduction to HIV.
17.2 HIV virion.
17.3 HIV genome.
17.4 HIV-1 replication.
17.5 HIV-1 variability.
17.6 Progression of HIV infection.
17.7 Prevention of HIV transmission.
18 Hepadnaviruses (and other reverse-transcribing DNA viruses).
18.1 Introduction to hepadnaviruses.
18.2 Importance of HBV.
18.3 HBV virion.
18.4 Non-infectious particles.
18.5 Soluble virus protein.
18.6 HBV genome.
18.7 HBV genetic groups.
18.8 HBV replication cycle.
18.9 Prevention and treatment of HBV infection.
18.10 Other reverse-transcribing DNA viruses.
19 Bacterial viruses.
19.1 Introduction to bacterial viruses (bacteriophages.
RNA PHAGES.
19.2 Single-stranded RNA phages.
19.3 Double-stranded RNA phages.
DNA PHAGES.
19.4 Single-stranded DNA phages.
19.5 Double-stranded DNA phages.
20 Origins and evolution of viruses.
21.1 Introduction to origins and evolution of viruses.
20.2 Origins of viruses.
20.3 Evolution of viruses.
21 Emerging viruses.
21.1 Introduction to emerging viruses
21.2 Viruses in new host species
21.3 Viruses in new areas
21.4 Viruses in new host species and in new areas
21.5 New viruses
21.6 Recently discovered virus
21.7 Re-emerging viruses
21.8 Virus surveillance
21.9 Dealing with outbreaks
22 Viruses and cancer
22.1 Introduction to viruses and cancer
22.2 Papillomavirus-linked cancers
22.3 Polyomavirus-linked cancers
22.4 Epstein-Barr virus-linked cancers
22.5 Kaposi’s sarcoma
22.6 Adult T cell leukaemia
22.7 Hepatocellular carcinoma
22.8 Virus-associated cancers in animals
22.9 Cell lines derived from virus-associated cancers.
22.10 How do viruses cause cancer?
22.11 Prevention of virus-induced cancers.
23 Survival of infectivity.
23.1 Preservation of virus infectivity.
23.2 Destruction of virus infectivity.
23.3 Inactivation targets in virions.
23.4 Inactivation kinetics.
23.5 Agents that inactivate virus infectivity.
24 Virus vaccines.
24.1 Introduction to virus vaccines.
24.2 Live attenuated virus vaccines.
24.3 Inactivated virus vaccines.
24.4 Virion subunit vaccines.
24.5 Live recombinant virus vaccines.
24.6 Mass production of viruses for vaccines.
24.7 Virus-like particles.
24.8 Synthetic peptide vaccines.
24.9 DNA vaccines.
24.10 Storage and transport of vaccines.
25 Anti-viral drugs.
25.1 Introduction to anti-viral drugs.
25.2 Development of anti-viral drugs.
25.3 Examples of anti-viral drugs.
25.4 Drug resistance.
25.5 Anti-viral drug research.
26 Prions.
26.1 Introduction to prions.
26.2 Transmissible spongiform encephalopathies.
26.3 The nature of prions.
26.4 Prion diseases.
26.5 Prion strains.
26.6 Prion transmission.
26.7 The protein-only hypothesis.
Learning outcomes.
Sources of further information
لینک دانلود
24 تير 1387
سلول های بنیادی مزانشیم Mesenchymal Stem Cells
Publisher: Humana Press | 2008-04-01 | 220 pages | ISBN:1588297713 |3.1 MB
For over forty years, mesenchymal stem cells (MSCs) have been scrutinized and studied, garnering much attention due to their broad therapeutic efficacy. In Mesenchymal Stem Cells: Methods and Protocols, leaders in the field were assembled to contribute detailed methodologies for the isolation and characterization of human and rodent MSCs. Recently, these vital cells have shown therapeutic benefits in the treatment of myocardial infarction, stroke, lung diseases, spinal cord injury and other neurological disorders, thus promising a boundless future in their study.
Cutting edge and easy to use, Mesenchymal Stem Cells: Methods and Protocols is the perfect resource for scientists attempting to pursue this important and ever-developing field of research.
لینک دانلود
24 تير 1387
راهنمای بیوانفورماتیک A Cell Biologist’s Guide to Modeling and Bioinformatics
A Cell Biologist’s Guide to Modeling and Bioinformatics
A step-by-step guide to using computational tools to solve problems in cell biology
Combining expert discussion with examples that can be reproduced by the reader, A Cell Biologist’s Guide to Modeling and Bioinformatics introduces an array of informatics tools that are available for analyzing biological data and modeling cellularalgebra and cellular biology; the author provides all the other tools you need to understand the necessary statistical and mathematical methods. processes. You learn to fully leverage public databases and create your own computational models. All that you need is a working knowledge of
Coverage is divided into two main categories:
Molecular sequence database chapters are dedicated to gaining an understanding of tools and strategies—including queries, alignment methods, and statistical significance measures—needed to improve searches for sequence similarity, protein families, and putative functional domains. Discussions of sequence alignments and biological database searching focus on publicly available resources used for background research and the characterization of novel gene products.
Modeling chapters take you through all the steps involved in creating a computational model for such basic research areas as cell cycle, calcium dynamics, and glycolysis. Each chapter introduces a new simulation tooland is based on published research. The combination creates a rich context for ongoing skill and knowledge development in modeling biological research systems.
Students and professional cell biologists can develop the basic skills needed to learn computational cell biology. This unique text, with its step-by-step instruction, enables you to test and develop your new bioinformatics and modeling skills. References are provided to help you take advantage of more advanced techniques, technologies, and training.
لینک دانلود
24 تير 1387
Animal Cell Culture Techniques
by Clynes M. "Animal Cell Culture Techniques (Springer Lab Manual)"
Springer-Verlag Telos | Pages: 618 | 1998-08 | ISBN: 3540630082 | Djvu | 4 Mb
Book Description:
Cell culture techniques allow a variety of molecular and cell biological questions to be addressed, offering physiological conditions whilst avoiding the use of laboratory animals. In addition to basic techniques, a wide range of specialised practical protocols covering the following areas are included: cell proliferation and death, in-vitro models for cell differentiation, in-vitro models for toxicology and pharmacology, industrial application of animal cell culture, genetic manipulation and analysis of human and animal cells in culture.
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23 تير 1387
What Can Nanotechnology Learn From Biotechnology
Academic Press | 2008-02-25 | ISBN: 012373990X | 360 pages | PDF | 1 MB
What Can Nanotechnology Learn From Biotechnology? presents diverse perspectives on biotechnology and nanotechnologies. Avoiding extreme perspectivesunwarranted hype and absolute rejectionthis book explores the diverse territory of proponents and opponents of challenging but potentially risky technologies. Contributions from recognized experts in their fields represent the perspectives of a diverse range of stakeholders.
This book details the lessons to be learned from the controversy over genetically modified foods, and how those lessons can be applied to developing nanotechnologies, particularly agricultural and other food-related applications. Exploring the environmental, social and ethical impact of nanotechnology in addition to the technical and economical impacts, it an ideal reference for any scientist, engineer, research program administrator, resource allocator, and NGO advocate.
Key Features:
*Addresses the growing concern over the responsibility of science to the impacted population
*Uses real-world experience to outline practical approaches for emerging technologies
*Addresses the concerns of science as well as social science
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23 تير 1387
Chromosomal Mutagenesis
Chromosomal Mutagenesis (Methods in Molecular Biology Volume 435)
Publisher: Humana Press | 2007-10-11 | 236 pages | ISBN:158829899X | 2.39 MB
Great disparities exist between organisms with regard to the relative ease of chromosomal mutagenesis and manipulation. In Chromosomal Mutagenesis, a team of experts provide a variety of chromosomal manipulation techniques, including insertional gene disruptions, gene knockouts, stimulated homologous recombination techniques and other novel tools, for both prokaryotic and eukaryotic organisms, and attempt to expand the genetic toolbox beyond model organisms. Following the format of the highly successful Methods in Molecular Biology format, each chapter offers step-by-step laboratory instructions, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Comprehensive and cutting-edge, Chromosomal Mutagenesis covers state-of-the-art techniques that are staged to expand, if not revolutionize, genetic analysis in the long neglected and relevant cell types.
23 تير 1387
Germline Stem Cells
Publisher: Humana Press | 2008-04 | 297 pages | ISBN:1603272135 | 6.6 MB
The knowledge gained by studying germline stem cells, the source of human and animal reproduction, may find immediate application in preserving endangered wildlife, managing commercial livestock, overcoming fertility problems in humans, and treating testicular and ovary tumors. In Germline Stem Cells, leading experts explore the parameters that define germline stem cells and the mechanisms that regulate the cell behavior in order to better isolate, characterize and maintain them. Divided into two parts, the volume begins by providing protocols for germline stem cell identification and regulation in model organisms, and concludes with detailed chapters covering current techniques involving in vitro culture and the applications of the cells.
Comprehensive and cutting-edge, Germline Stem Cells is the perfect reference for scientists exploring this particular exciting and important subdivision in the fast-paced field of stem cell research
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20 تير 1387
Stem Cells and Myocardial Regeneration
Author: Penn, M
Delivery Type: Physical
Edition/Volume: 01
Inventory Status: On Order With Supplier
Publisher: Humana Press
Pages: 315
Type: EBook
Format:PDF
Published Date: 10/01/2006
Product Id: 61382
Size:۲.۸ MB
Editorial Reviews
Stem Cells and Myocardial Regeneration is a comprehensive bench to bedside examination of stem cell-based therapies for cardiac dysfunction. The contributors, all leading researchers in their area of expertise, explore recent advances in the laboratory and in clinical trials. This volume emphasizes the near epidemic status of chronic heart failure (CHF) in the United States and abroad, and evaluates the level of success and failure of current optimal medical therapy. Specific attention is also given to both the basic cell types and pathways involved in cardiac stem cell research and the clinical issues that surround it.
Parts I and II of Stem Cells and Myocardial Regeneration examine various cardiac stem cell types, including hematopoietic, mesenchymal, and endogenous cells and critical physiological pathways, including chemokines, stem cell differentiation, and arrhythmia mechanisms. Part III focuses on clinical issues intrinsic to delivery of stem cells to the heart at the time of myocardial infarction (MI) and in patients with CHF. Part IV contains up-to-date reviews and analyses of the findings of stem cell-based clinical trials of acute MI and CHF. The concluding section presents a summary of cardiac stem cell research and outlines potential obstacles to future study
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